Dartmouth scientists have delved into how different bacterial species coexist within biofilms, which are notorious for causing infections that are hard to treat. This captivating microscopy image displays a biofilm featuring three bacterial types under study: Pseudomonas aeruginosa (yellow), Escherichia coli (pink/purple), and Enterococcus faecalis (blue/green). The research revealed that P. aeruginosa takes charge initially but retreats when overcrowding occurs, allowing space for other species to flourish until it reclaims dominance.
Biofilms, those slimy bacterial communities found everywhere from natural environments to medical devices like catheters, often consist of multiple bacterial strains whose interactions remain mysterious.
In a groundbreaking study published in Current Biology by Dartmouth researchers, experiments and models shed light on how these bacteria manage to coexist within biofilms while also exploring their individual behaviors.
Pseudomonas aeruginosa stood out as a dominant force among three studied bacteria strains due to its antibiotic resistance capabilities. However, rather than engaging in competition with its counterparts when conditions became cramped, this bacterium opted for migration towards more favorable surroundings—a move that ultimately benefited the entire community of bacteria.
Lead author Jacob Holt emphasized how understanding these dynamics is crucial given that all three bacterial strains examined—P. aeruginosa, Escherichia coli, and Enterococcus faecalis—are opportunistic pathogens commonly associated with urinary tract infections linked to catheter use.
The findings underscored the significance of dispersal behavior in shaping microbial communities within biofilms—a critical insight into combating challenging infections caused by these resilient pathogens.
2024-10-17 13:15:03
Link from phys.org
