Unveiling the Enigma of Phosphite: A Scientific Investigation Unearths a Novel Bacterial Metabolism

Unveiling the Enigma of Phosphite: A Scientific Investigation Unearths a Novel Bacterial Metabolism

Konstanz biologists have made a fascinating discovery involving a phosphorus-based bacterial metabolism that is both new and ⁣ancient.⁢ The story ‌of this discovery involves a calculation made in the 1980s, a sewage plant, a‍ newly found bacterial organism,⁤ and a remnant from⁤ approximately 2.5 billion years ago.

The narrative begins in​ the ⁢late 1980s with a scientist who made a calculation on a sheet ⁣of paper. The calculation showed that the ‌conversion of phosphite⁢ to phosphate could release enough energy to produce the cell’s energy carrier,‌ the ATP molecule. This meant⁢ that ⁢it was possible for a microorganism to generate its own energy without ‌relying on light or the⁣ decomposition of organic matter, unlike most ​other organisms on Earth.

The scientist successfully isolated such a microorganism from the environment. Its energy metabolism is based on‌ the oxidation of phosphite to phosphate, just as the calculation had predicted. However, the biochemical mechanism behind this⁢ process remained a mystery for many years⁤ because⁣ the key enzyme needed to ​understand it remained hidden.

For ⁢the next three decades, the sheet of ⁣paper remained in a drawer, and the research on this topic was put on​ hold. However, the scientist couldn’t stop thinking about it. The scientist in question is Bernhard Schink, a professor at the Limnological Institute of the University of ​Konstanz. After three decades, an unexpected discovery reignited the research.

2023-11-10 11:41:04
Link from phys.org

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