The novel phenothiazine photocatalysts have strong reducing ability and higher stability and recyclability than existing phenothiazine catalysts, representing a promising tool for achieving sustainable organic synthesis. Credit: Kenta Tanaka, Okayama University
In recent years, global environmental concerns have prompted a shift toward eco-friendly manufacturing in the field of organic synthetic chemistry. In this regard, research into photoredox catalytic reactions, which use light to initiate redox or reduction-oxidation reactions via a photoredox catalyst, has gained significant attention. This approach reduces the reliance on harsh and toxic reagents and uses visible light, a clean energy source.
A key research area has been the development of recycling methods for photocatalysts, which offer both economic and environmental benefits. Photocatalysts use light to accelerate a chemical reaction without getting consumed in the process, and photoredox catalysts are photocatalysts specifically designed for redox reactions.
While recycling methods for heterogeneous photocatalysts, such as semiconductors and polymers, have been widely developed, there has been less focus on recycling organic photocatalysts. Considering the cost-effectiveness and low toxicity of organic photoredox catalysts, developing suitable recycling approaches is essential for achieving sustainable organic synthesis.
Addressing this gap, a team of researchers from Okayama University, Japan, including Assistant Professor Kenta Tanaka from the Research Institute for Interdisciplinary Science, along with then-graduate student Haru Ando, Associate Professor Hiroyoshi Takamura, and Professor Isao Kadota from the Department of Chemistry at the Graduate School of Natural Science and Technology, developed a novel phenothiazine-based organic photoredox catalyst. Their study was published in the journal Chemical Communications on March 19, 2024.
“Phenothiazines, or PTHs, are widely used as photocatalysts in organic chemistry,” explains Prof. Tanaka. “However, the high reactivity of the p-position relative to the nitrogen atom on 10-aryl phenothiazine molecules, makes them prone to reacting with electrophiles, reducing their stability.
“The development of more stable and sustainable photocatalysts is therefore highly desirable. To address this, we developed new phenothiazine-based photocatalysts that is both stable and recyclable.”
2024-05-24 17:51:02
Original from phys.org