Unlocking the Potential: How a Widely Used Medication Could Revolutionize Treatment for a Rare Genetic Disorder

Unlocking the Potential: How a Widely Used Medication Could Revolutionize Treatment for a Rare Genetic Disorder




DENVER ⁣— Researchers​ have discovered​ a potential treatment for⁣ a rare genetic disorder using a common drug found in ⁤most medicine cabinets. ‌The disease, ⁣known ‌as MAN1B1-congenital disorder ​of glycosylation, is caused by mutations in the MAN1B1 gene, leading to⁣ developmental ⁣delays and ​various ⁣health issues.
With no current‍ cure available, ​scientists conducted a study ⁢to ‍repurpose existing ⁢drugs for treatment.‌ By testing over ⁣1,500 approved ‍medications on ​fruit ‌flies with mutated MAN1B1 genes, ‍they identified 51 drugs⁤ that restored normal eye development and ⁢function. Surprisingly, nine of these drugs were‌ nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen.
This innovative approach offers hope for individuals with rare ​diseases who cannot afford to wait decades⁣ for new treatments to be developed.

2024-11-08 15:31:35
Source from www.sciencenews.org

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