CHICAGO — A recent study reveals that mice on the diabetes and weight-loss drug semaglutide, known as Ozempic and Wegovy, showed reduced interest in running on a wheel. This finding sheds light on the drug’s impact on exercise behavior in rodents. Neuroscientist Karolina Skibicka from Penn State University and the University of Gothenburg in Sweden emphasizes the significance of this discovery, highlighting that there is still much to learn about these drugs’ effects.
Mice typically run up to 10 kilometers a day when given free access to a running wheel, according to neuroscientist Ralph DiLeone from Yale University. However, when administered semaglutide for seven days, both male and female mice ran approximately 38 percent less than usual. Interestingly, once off the drug, their running activity returned to normal levels.
2024-10-07 14:37:58
Originally posted on www.sciencenews.org