Researchers at Tokyo Institute of Technology and Kyushu University have developed a new solvatochromic probe that could provide valuable insights into the connection between lipid membrane fluidity and various cellular processes. This innovative probe offers exceptional stability, low toxicity, and outstanding fluorescent properties, enabling real-time visualization of changes in lipid membrane order during complex activities like cell division.
Lipid membranes are not just barriers; they also play crucial roles in cell movement, material exchange, waste management, and sensing. Proteins and other molecules integrated into the membrane structure influence its fluidity and order, making the study of lipid membrane order an important area in cellular biology.
To observe lipid membrane fluidity, scientists typically use solvatochromic probes or dyes, which emit light of varying colors based on the polarity of the surrounding environment. However, traditional solvatochromic dyes have limitations such as low stability, weak fluorescent emissions, cell toxicity, and reliance on ultraviolet light for excitation.
2024-03-13 08:00:04
Source from phys.org